What Is Functional Medicine?
A Root-Cause Approach to Lasting Health
Our bodies are not merely a collection of independent parts; they are interconnected systems that work together in harmony. Yet, when it comes to chronic diseases—such as diabetes, heart disease, arthritis, gastrointestinal conditions, thyroid disorders, and dementia—traditional healthcare often focuses on temporary treatments rather than addressing, preventing, and treating the underlying causes. In fact, these chronic conditions account for 78% of our total healthcare efforts, despite the fact that many are preventable.
A Different Approach to Healthcare
Functional medicine is a science-based, patient-centered approach to healing that focuses on identifying and addressing the root causes of disease rather than just treating symptoms. Instead of offering a one-size-fits-all solution, functional medicine considers an individual’s genetics, environment, and lifestyle to create a personalized plan for optimal health.
Key Principles of Functional Medicine
-
Root-Cause Resolution – Instead of merely managing symptoms, functional medicine seeks to uncover the deeper imbalances that drive disease, whether it’s inflammation, gut dysfunction, hormonal imbalances, or nutritional deficiencies.
-
Personalized Care – Every person’s body is unique, which means treatments should be tailored to the individual. Functional medicine practitioners take a deep dive into a patient’s medical history, lifestyle, diet, and genetics to develop a customized plan.
-
Holistic Healing – The body functions as an interconnected whole. Functional medicine considers how different systems—like the gut, brain, hormones, and immune system—work together to influence health.
-
Lifestyle and Prevention – Functional medicine prioritizes preventive care by addressing diet, stress management, sleep quality, and physical activity to promote long-term well-being.
Conditions Treated with Functional Medicine
Functional medicine addresses a wide range of chronic and complex conditions, including:
-
Hormonal Imbalances – Menopause, perimenopause, thyroid disorders, adrenal dysfunction, and polycystic ovary syndrome (PCOS).
-
Digestive Disorders – Irritable bowel syndrome (IBS), small intestinal bacterial overgrowth (SIBO), Crohn’s disease, ulcerative colitis, and leaky gut.
-
Metabolic and Endocrine Conditions – Diabetes, insulin resistance, metabolic syndrome, and weight management challenges.
-
Autoimmune Diseases – Rheumatoid arthritis, lupus, Hashimoto’s thyroiditis, multiple sclerosis, and celiac disease.
-
Neurological and Mental Health Concerns – Brain fog, anxiety, depression, migraines, and neurodegenerative diseases like Alzheimer’s.
-
Chronic Fatigue and Fibromyalgia – Addressing underlying causes of fatigue, muscle pain, and systemic inflammation.
-
Cardiovascular Health – High blood pressure, high cholesterol, and heart disease prevention.
-
Allergies and Immune Dysfunction – Chronic sinusitis, food sensitivities, and immune system imbalances.
Functional Medicine in Practice
At O'Keefe Matz Functional Health Clinic in Saint Paul, MN, we use functional medicine to help patients find relief from chronic conditions and regain their vitality. Our approach includes:
-
Advanced Lab Testing – We go beyond conventional lab tests to identify nutritional deficiencies, hormone imbalances, and inflammation markers.
-
Nutritional and Dietary Strategies – Food is medicine. We create tailored nutrition plans to heal the body at a cellular level.
-
Gut Health Optimization – A healthy gut is the foundation of overall health. We focus on repairing digestive function and restoring beneficial gut bacteria.
-
Hormone Balancing – From menopause and thyroid disorders to adrenal dysfunction, we help patients restore hormonal equilibrium naturally.
-
Detoxification Support – We guide patients through safe and effective detox strategies to reduce toxic burden and promote cellular health.
Transform Your Health with Functional Medicine
If you’re tired of masking symptoms with medications and want a deeper, more comprehensive approach to healing, functional medicine could be the answer.
At O'Keefe Matz Functional Health Clinic, we are proud to have Dr. Shannon O'Keefe, a passionate, driven, and highly skilled expert in Functional Medicine and Internal Diagnosis. Dr. O’Keefe is deeply committed to helping her patients achieve true wellness by uncovering the root causes of their health concerns. Her compassionate and thorough approach ensures that every patient feels heard, valued, and supported on their healing journey. With years of experience and a relentless dedication to improving lives, Dr. O’Keefe blends cutting-edge science with holistic strategies to create real, lasting transformations in health and well-being.
If you’re in Saint Paul, MN, and looking for a more personalized, holistic approach to healthcare, contact us today to schedule a consultation. Take control of your health and start your journey to a better, healthier you!
Check Out Our Trailer for Functional Medicine: Getting to the Underlying Cause of Disease Video Series
In this health talk, Dr. Shannon O’Keefe offers a roadmap to lasting health by helping you understand the root causes of chronic illness and what can be done to prevent them. Contrary to common belief, chronic diseases are not solely dictated by genetics; rather, they result from a misalignment between our genes, environment, and lifestyle. With the implementation of a personalized health program, many chronic diseases can be rendered obsolete. This presentation, originally delivered to the MN Holistic Nurses Association, is invaluable for anyone interested in a comprehensive approach to health. Attendees will gain insight into the benefits and rewards of adopting a functional medicine approach, empowering them to take control of their well-being and achieve long-term health.
Functional Medicine, Part 1
Functional Medicine, Part 2
Functional Medicine, Part 3
Functional medicine/Internal Medicine addresses the underlying causes of disease, using a systems-oriented approach and requires participation from both the patient and practitioner. Shifting away from the traditional “sick-care model” to a more patient-centered approach, functional medicine addresses the whole person, not just an isolated set of symptoms. As Functional Medicine practitioners, we spend time listening to our patients, asking many questions, and looking at the interactions among genetic, environmental, and lifestyle factors that can influence long-term health and complex, chronic disease. https://improveurhealth.com/functional-medicine-clinical-nutrition/
Dr. Shannon A. O'Keefe
Book NowDr. O'Keefe Speaking on AutoImmune Conditions
Empower your Journey with Natural Medicine
Check Out Our Trailer for our Osteoporosis Video Series
Osteoporosis - Part 1
Osteoporosis - Part 2
Osteoporosis - Part 3
Blog
Functional Medicine & Internal Medicine Diagnosis
Get to the Underlying Cause of your Condition. Health Is Everything!
Diagnostic Laboratory testing
Don't Guess about your Health, Get tested.

Functional Testing and Homeostatic Evaluations
Menu of tests we offer
We utilize a large variety of testing in order to get to the underlying cause of your symptoms.
MENU OF TESTS
Comprehensive blood work
Cardio vascular profiles
Autoimmune panels
Inflammation panels
Food sensitivity testing
Leaky Gut/Intestinal Permeability
Gluten Cross Reactivity
Secretary IgA
Stool analysis: Parasitology, microbiology and yeast
SIBO
Female hormones
Adrenal Hormones
Neurotransmitters
Amino Acids
Heavy Metals
Blood Brain Barrier
LYME
Urinalysis
Methylation Profiles
Urine Porphyrins
Nutrient Evaluations
Iodine
RBC glutathione
Fatty Acids
Bone Resorption Assessments
Melatonin
H. Pylori
Male Hormones
PSA free and total
Organic Acids
O'Keefe Matz Chiropractic & Functional Health Clinic
1053 Ashland Ave,Saint Paul, MN
55104 View Staff & Treatments